Adaptive optics (AO) imaging has brought unique possibilities for assessing retinal blood vessels, thanks to direct visualizations of capillaries and vessel walls.
Based on high-resolution AO images, multiple biomarkers have been studied to quantify microvascular alterations in a number of diseases, including arterial hypertension and diabetes.
What do these biomarkers measure? How relevant are they? How far have they been evaluated? These questions have recently been answered in a review article published (In Press) in Survey of Ophthalmology.
Several of these microvascular metrics are readily available to clinicians in the rtx1™ Adaptive Optics Retinal Camera.