Complete set
of adaptive optics components
The AO toolbox for ophthalmic device developers
Imagine Eyes’ adaptive optics (AO) components deliver unparalleled performance for measuring ocular wavefront errors, simulating ophthalmic lenses, and enhancing optical resolution of retinal imaging systems.
They enable an AO technology which performs flawlessly when applied to living eyes, and can readily be incorporated in various system configurations.
The AOkit™ is a complete set of AO components specially designed for industrials and researchers who develop ophthalmic instrumentation. It includes:
- the mirao™ 52-e deformable mirror
- the HASO™4 first wavefront sensor
- WaveTune™ AO control software
Each component of the AOkit ideally complements each other, and all of them are seamlessly integrated in a broad variety of systems.
Optimal performance
for use with living eyes
Seamless integration
in a broad variety of opthalmic systems
mirao 52-e
The best performance with living eyes
The mirao 52-e uses a patented electromagnetic actuation technology to deform a highly-reflecting membrane. It enables compensating for the wide variety of wavefront errors that affect living eyes with high accuracy. Even eyes suffering from high astigmatism are fully corrected by the mirao 52-e.
It is seamlessly integrated thanks to plug-and-play USB connectivity, small footprint, and compliance with electrical safety and electromagnetic compatibility standards (IEC 61010-1, IEC 61326-1 and IEC 60601-1-2).
It can be operated without the need for developing software when used in combination with the HASO4 first wavefront sensor and WaveTune software. Additionally, for software developers, a complete application programming interface (API) is included with the mirao 52-e product.
mirao 52-e
The best performance with living eyes
The mirao 52-e uses a patented electromagnetic actuation technology to deform a highly-reflecting membrane. It enables compensating for the wide variety of wavefront errors that affect living eyes with high accuracy. Even eyes suffering from high astigmatism are fully corrected by the mirao 52-e.
It is seamlessly integrated thanks to plug-and-play USB connectivity, small footprint, and compliance with electrical safety and electromagnetic compatibility standards (IEC 61010-1, IEC 61326-1 and IEC 60601-1-2).
It can be operated without the need for developing software when used in combination with the HASO4 first wavefront sensor and WaveTune software. Additionally, for software developers, a complete application programming interface (API) is included with the mirao 52-e product.
HASO4 first
Advanced wavefront sensor
Based on patented Shack-Hartmann technology, the HASO4 first includes a 1280 high-quality micro-lens array in a 3.6 x 4.5 mm² pupil. It provides outstanding performance by combining high precision (λ/100) and large measuring range (defocus up to 66 D), which together enable to accurately assess the wide variety of wavefront aberrations that affect living eyes.
Its ergonomic design and the USB 3.0 connectivity allow an easy plug and play installation. Delivered with WaveView wavefront metrology software, it takes only a few clicks to perform wavefront measurement, wavefront reconstruction, or to visualize the spot image and raw camera data.
In ophthalmic adaptive optics systems, the HASO4 first ideally complements the mirao 52-e deformable mirror and WaveTune software.
WaveTune software
New approach for adaptive optics
WaveTune, the successor of Casao™, is a unique application that combines wavefront measurement and correction features with extensive instrument calibration and diagnostics functions. It provides an ergonomic, all-in-one adaptive optics PC workspace.
Included in Imagine Eyes’ AOkit, WaveTune is perfectly adapted to the mirao 52-e deformable mirror and the HASO4 first wavefront sensor. In many cases, it is the only software tool that you need to drive your AO system in both closed and open loop.
Whether you’re an established expert in adaptive optics or just getting started, you’ll be up and running quickly thanks to WaveTune’s user-friendly, feature rich environment.
WaveTune software
New approach for adaptive optics
WaveTune, the successor of Casao™, is a unique application that combines wavefront measurement and correction features with extensive instrument calibration and diagnostics functions. It provides an ergonomic, all-in-one adaptive optics PC workspace.
Included in Imagine Eyes’ AOkit, WaveTune is perfectly adapted to the mirao 52-e deformable mirror and the HASO4 first wavefront sensor. In many cases, it is the only software tool that you need to drive your AO system in both closed and open loop.
Whether you’re an established expert in adaptive optics or just getting started, you’ll be up and running quickly thanks to WaveTune’s user-friendly, feature rich environment.
Proven performance in ophthalmic applications
Imagine Eyes’ products are the most integrated AO components in ophthalmic instruments, including the rtx1, the first adaptive optics retinal camera on the market.
These components have also been successfully implemented in multiple wavefront aberrometers and vision simulators, as well as in a number of retinal imaging instruments in combination with various imaging modalities such as scanning laser ophthalmoscopes (SLO) and optical coherence tomography (OCT).
Links & Downloads
mirao 52-e
datasheet
HASO4 first
brochure
WaveSuite
brochure
Specifications
| Deformable mirror | mirao 52-e |
| Number of actuators | 52 |
| Maximum generated wavefront (PV) | ±50 µm |
| Surface quality (rms active flat) | 10 nm |
| Integrated tip/tilt correction | yes |
| Spatial frequency correction Zernike orders | up to 6 |
| Effective diameter | 15 mm |
| Linearity | > 95% |
| Hysteresis | < 2% |
| Actuator input voltage | ±1V maximum 1 |
| Coating | protected silver |
| Power consumption | 50W max |
| Dimensions / weight | 64 x 64 x 23 mm / 490g 2 |
| Connectivity | USB 2.0 |
| Operating System | Windows XP, 7 (x32 – x64 under evaluation) |
1 Total sum of applied voltages not to exceed 25V.
2 Mirror unit only.
| Wavefront sensor | HASO4 first |
| Aperture dimension | 3.6 x 4.6 mm² |
| Number of microlenses | 32 x 40 |
| Tilt dynamic range | > ± 3 ° (400 λ) |
| Focus dynamic range | ± 0.018 m to ± ∞ (350 λ) |
| Focus dynamic range – maximum NA | 0.1 |
| Repeatability (rms) | < λ/200 |
| Wavefront measurement accuracy in relative mode (rms)1 | ~ λ/150 |
| Wavefront measurement accuracy in absolute mode (rms)2 | ~ λ/100 |
| Tilt measurement sensitivity (rms) | 5 μrad |
| Focus measurement sensitivity (rms) | 3·10-3 m-1 |
| Spatial resolution | ~ 110 μm |
| Maximum acquisition frequency | 100 Hz |
| Processing frequency (CPU 3Ghz, 512 Mb RAM) | 20 Hz |
| Working wavelength range | 350 – 1100 nm |
| Calibrated wavelength | in the 400-1100 nm range, details on request3 |
| Dimensions / weight | 42x 42 x 42 mm /150g |
| Interface / Power supply | USB 3.0 / 2.7 W via USB |
| Operating system | Win 7 (x86 / x64) |
| External trigger | yes |
1 Wavefront as seen by the device.
2 Difference between the real wavefront and a reference wavefront obtained in similar conditions (5λ of shift max).
3 Single wavelength calibration (+- 50 nm), second wavelength calibration available on request.
mirao is a trademark of Imagine Eyes SA. HASO and WaveTune are trademarks of Imagine Optic SA.
Contact us for more information
In all patients, AO images showed dark elements that were smaller than what could be resolved by fundus imaging and OCT
Bek. Acta Ophthalmologica 92, 753–758
The rtx1 demonstrates that, unlike the common belief, performing AO retinal imaging can be as easy as standard retinal imaging
Pr. Paques, Quinze-Vingt National Hospital July 2018, Paris, France
We, for the first time, visualized longitudinal changes during the recovery of cone photoreceptors in the eyes of VKH patients
Nakamura et al. Graefes Arch Clin Exp Ophthalmol (2018) 256:387
The image resolution achieved by this technology is superior to that of any other current diagnostic tool.
Zaleska-Zmijewska et al.Journal of Diabetes Research 2017, 1–9
Adaptive optics retinal imaging provided non-invasive and sensitive information on the pathologic disruption of the cone mosaic, even in the absence of subjective (visual loss) or objective (diagnostic imaging) abnormalities.
Ziccardi, L. et al. American Journal of Ophthalmology 160, 301–312.e6
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