comfortable for patients
When using the rtx1 Adaptive Optics Retinal Camera, you examine the retina at a scale where individual cells are visible. Its ultrahigh-resolution images reveal parafoveal cone photoreceptors as well as other microscopic retinal structures that cannot be seen with conventional techniques.
The rtx1 enables visualizing the microscopic walls of retinal arterioles non-invasively. Focal narrowing, perivascular sheathing, micro-hemorrhages and micro-aneurisms are also visible without using contrast agents.
The TFI option introduces transscleral illumination in the rtx1 AO camera, to reveal retinal structures that are otherwise not visible with rtx1. It enables new explorations of the retinal pigmented epithelium layer and its changes at the microscopic scale.
comfortable for patients
with micrometer precision
quantify small retinal changes
in a wide range of pathologies
Successfully imaging photoreceptor and RPE cells has become essential in an era of gene therapy and complement modulation.
TFI could be a valuable addition to a conventional trans-pupillary flood-illumination AO camera, not only for seeing the RPE cells, but also for detecting clinical features such as pigment clumps.
By design, the rtx1 delivers images that are free from motion distortion. Building on this advantage, its software enables capturing the same retinal region through different visits, and automatically aligns follow-up images. This allows tracking minute changes in a group of cells, a vessel section, or a lesion over time.
With AOdetect application, rtx1 delivers an array of candidate biomarkers for assessing the distribution of parafoveal cone cells :
On follow-up images, AOdetect enables analyzing the exact same region of interest, for monitoring a given group of cells over time.
AOdetect application also provides supervised image segmentation for analyzing the wall morphology of blood vessels. With this option, rtx1 delivers non-invasive vascular structure metrics with micrometer precision:
The exact same vascular section is assessed on follow-up images with a only a few clicks.
The time when AO technology could only be mastered by physicists and engineers belongs to the past. Designed in collaboration with clinicians, the rtx1 is driven by user-friendly software which enables high patient throughput. It is also comfortable for patients as image acquisition uses infrared illumination and only takes 2 seconds.
The rtx1 stands out as the most widely-used AO imaging device in medical centers throughout the world. Cleared by regulatory authorities in several countries, and proven by over 200 peer-reviewed publications, it has become the reference product for cellular-resolution retinal imaging.
|Imaging type||En face reflectance imaging|
|Detection type||Low-noise CCD camera|
|Illumination||Near infrared LED, 850nm|
|Exposure time||< 10 ms|
|Imaging field of view 1||4° x 4°|
|Fixation stimulation range||H ± 14.5° / V ± 10°|
|Camera pixel pitch on the fundus 1||1.1 µm|
|Optical resolution on the fundus 1, 2||250 line pairs per millimeter (lppmm)|
|Adaptive optics control||Fully automated, resistant to blinking and movement|
|Depth focussing range 1||1600 µm|
|Pupil diameter||≥ 4 mm|
|Refractive error compensation||-12 to +6 D|
|Total footprint (WxDxH)||137x53x132-162 cm|
1 Some specifications are dependent on several factors including but not limited to: ocular biometry, pupil diameter, optical defects, ocular media transparency.
2 The system can image line pairs of 2 µm in line width.
rtx1 is a certified medical device of class IIa in the European Union. rtx1 is an approved medical device in Japan, China and Korea. In the USA, rtx1 has not received FDA clearance; it is an investigational device that requires Institutional Review Board (IRB) oversight.
AOdetect is an option of the certified rtx1 device in the European Union, Japan and Korea. TFI is an option of the certified rtx1 device in the European Union. In other territories, AOdetect and TFI are separate products for research use only.
For use by trained eyecare professionals only.
All retinal images on this page are courtesy of: Quinze-Vingts National Eye Hospital, Paris, France.