Euretina 2021 – Progression rate of retinitis pigmentosa measured over 6 months


OCT imaging has been the standard method for assessing the structural progression of retinitis pigmentosa (RP). With this technique, it takes 12 to 24 months to detect retinal changes caused by RP.

At Euretina 2021, researchers at the Lions Eye Institute, Australia, present a longitudinal study that assessed the progression of RP with both OCT and an adaptive optics retinal camera (rtx1, Imagine Eyes).

Over a period of 6 months, no change was measurable with OCT, while adaptive optics images revealed an 11% drop in cone photoreceptor density on average.

The authors concluded “Parafoveal cone density should be considered as an endpoint in future natural history studies and clinical trials in RP”.

Parafoveal Cone Density Change in Retinitis Pigmentosa over Six Months

Poster #9258 by Danial Roshandel