Clinical and animal findings with adaptive optics retinal cameras

In recent years, not only clinical investigators, but also animal researchers have increasingly adopted the rtx1 AO camera to make new discoveries and assess new therapies at the cellular level in the retina.

Both types of users have reported significant new findings at ARVO 2021 last week. Our team at Imagine Eyes is grateful for such a great exposure, and happy to share the present summary.

For ARVO attendees, posters and replays are available until June 30th.

Clinical findings:

  • Freidericke Kortüm at the Univeristy of Tübingen reported rapid changes in the photoreceptor morphology after successful gene therapy in a patient with Leber congenital amaurosis type 2. Watch the replay
  • Amisha Dave at the National Institutes of Health demonstrated highly repeatable cone density measurements in retinitis pigmentosa. Watch the replay
  • Marie Elise Wistrup Torm at the University of Copenhagen revealed new phenotype information at the cellular level in a case of Niemann-Pick disease. See the poster
  • In multiple sclerosis, Stephanie McIlwaine at the Queens University of Belfast found significant reductions of cone density, even in retinas where OCT showed no outer retinal damage. See the poster
  • In patients with ADOA, Christina Eckmann-Hansen at the University of Copenhagen revealed microcystic lesions that were invisible with OCT. See the poster
  • Wataru Matsumiya at the University of Stanford reported significant correlations between cone density and microperimetry assessed in autoimmune retinopathy. See the poster
  • Daniela Castro Farias at Paris Quinze-Vingt Hospital presented new assessments of neurovascular coupling with micrometer accuracy using an AO retinal camera. See the poster

Animal findings:

  • In a monkey model of retinitis pigmentosa, Martha Neuringer at the Oregon Health and Science University measured the progressive increase in cone density that occurs through the first months of life. Watch the replay
  • Rishabh Gupta at the National Institutes of Health demonstrated in vivo analyzes of cone density in a porcine model mimicking AMD. See the poster

Join us for new discoveries

Contact us here