Clinical study with rtx1 reveals visual cell loss in Bestrophinopathy

Autosomal recessive bestrophinopathy (ARB) is an inherited retinal disease which causes losses in central vision. New insights are given in an article published by Dr Shinji Ueno and other medical researchers at the Nagoya University Graduate School of Medicine, Japan.

They report that the rtx1 Adaptive Optics Retinal Camera revealed significant abnormalities in retinal photoreceptor cells in 5 patients with ARB. Cone cell density was markedly reduced compared to healthy controls, even in patients whose visual acuity was good at the time of examination (BCVA> 20/25).

The authors conclude that “Monitoring cone photoreceptors by adaptive optics fundus imaging should provide accurate assessments of the disease status and indications for future therapeutic interventions.”

Article reference: Nakanishi, A. et al. Changes of Cone Photoreceptor Mosaic in Autosomal Recessive Bestrophinopathy. Retina. DOI: 10.1097/IAE.0000000000002363 (2018)

Read more about the rtx1 Adaptive Optics Retinal Camera
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