Adaptive optics monitors photoreceptor response to therapy in multifocal choroiditis

Recently published in Retinal Cases & Brief Reports, a longitudinal case study describes the course of retinal alterations caused by multifocal choroiditis, in a patient treated with anti-VEGF and steroid therapies.

Over a follow-up period of nine months, retinal imaging with adaptive optics (rtx1 camera) revealed a progressive recovery of cone photoreceptors in lesion areas.

“In this article, we demonstrate that adaptive optics imaging can be used to provide further information regarding the nature and activity of inflammatory choroidal lesions, which correlate to functional changes on microperimetry.”

 

Article reference: Amarasekera, S., Williams, A. M., Freund, K. B., Rossi, E. A., & Dansingani, K. K. (2022). Multimodal Imaging of Multifocal Choroiditis with Adaptive Optics Ophthalmoscopy. Retinal Cases and Brief Reports, 16(6), 747‑753. https://doi.org/10.1097/ICB.0000000000001134